Preventing Medication Errors in the Home

Posted by on Oct 7, 2011 in Medication for Alzheimer's | 0 comments

Medication errors have become a national issue. At least 1.5 million people are harmed annually with a containment cost of 3.5 billion dollars spent to treat drug related injuries. Dementia patients living at home must be recognized as being particularly more vulnerable to medication errors.

In the care environment of a patient’s home, there are a multitude of unique variables that may contribute to the challenge of assuring medication errors do not occur. Challenges present themselves for our visually impaired patients, patients who live alone, patients with multiple medications, and the lack of an individual caregiver who can assume the role for medication administration in order to ensure complete adherence to the prescribed regimen.

A medication error is defined as “any preventible event that may cause or lead to inappropriate medication use or patient harm when the medication is in the control of the patient, or consumer”.

ElderCare at Home’s field staff are responsible for assuring the patient’s five rights are assured: right patient, right medication, right dose, right route, and right time. Knowledge of each individual patients allergies, medication indications, and contradictions, as well as any adverse reactions, is a basic responsibility of all our practicing nurses.

To find out how our medication management programs can help you or someone you care for, contact us at 800-209-4342.

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Early-Onset Familial Alzheimer’s Disease

Posted by on Sep 18, 2011 in Early-Onset Familial Alzheimer Disease | 0 comments

Early-onset familial Alzheimer disease is hereditary and marked by Alzheimer disease symptoms that appear at an unusually early age. Symptoms can start in a person’s thirties, forties, and fifties and very rarely in the late twenties. Generally, if you are diagnosed with early-onset familial Alzheimer’s disease, then one of your parents will also have had it if he or she lived long enough, and your siblings and your children may have a 50-50 chance of having inherited it. Very rarely, early-onset familial Alzheimer’s disease can make a first-time appearance in a family through a new genetic mutation.
Apart from the differences in genetic cause and age of onset, neurologists generally agree that early-onset familial Alzheimer’s disease and late-onset Alzheimer’s disease are essentially the same disease. Early-onset familial Alzheimer’s disease progresses with the same overall sequence of symptoms and increasing impairments as that of late-onset Alzheimer’s.
Like the more common late-onset Alzheimer’s disease, early-onset familial Alzheimer’s disease is incurable. Over several years, the patient will lose memory and other mental functions, and become completely dependent on others. At this time, there is no treatment to slow down the disease.
Two things stand out the most about early-onset familial Alzheimer’s disease. One is how the Alzheimer’s disease clinical syndrome develops in an otherwise healthy personand the other is how high a burden the disease imposes on the spouse and children, who are often still young. These patients are active, working people who are in the midst of building a life for their families.

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The Genetic Component of Early Onset Alzheimer’s Disease

Posted by on Sep 4, 2011 in diagnosis, Early Onset Alzheimer's Disease | 0 comments

Early-onset Alzheimer’s disease occurs in people age 30 to 60. It is rare, representing less than 5 percent of all people who have Alzheimer’s. Some cases of early-onset Alzheimer’s have no known cause, but most cases are inherited, a type known as familial Alzheimer’s disease (FAD).

Familial Alzheimer’s disease (FAD)  is caused by any one of a number of different single-gene mutations on chromosomes 21, 14, and 1. Each of these mutations causes abnormal proteins to be formed. Mutations on chromosome 21 cause the formation of abnormal amyloid precursor protein (APP). A mutation on chromosome 14 causes abnormal presenilin 1 to be made, and a mutation on chromosome 1 leads to abnormal presenilin 2.

Scientists know that each of these mutations plays a role in the breakdown of APP, a protein whose precise function is not yet known. This breakdown is part of a process that generates harmful forms of amyloid plaques, a hallmark of the disease. A child whose mother or father carries a genetic mutation for FAD has a 50/50 chance of inheriting that mutation. If the mutation is in fact inherited, the child almost surely will develop FAD.

Critical research findings about early-onset Alzheimer’s have helped identify key steps in the formation of brain abnormalities typical of Alzheimer’s disease. They have also led to the development of imaging tests that show the accumulation of amyloid in the living brain. In addition, the study of Alzheimer’s genetics has helped explain some of the variation in the age at which the disease develops.

Scientists are continuing research through the Dominantly Inherited Alzheimer Network (DIAN), an international partnership to study families with a genetic mutation that causes early-onset Alzheimer’s disease.

By observing the biological changes that occur in these families long before symptoms appear, scientists hope to gain insight into how and why the disease develops in both its early- and late-onset forms. In addition, scientists are attempting to develop tests that will enable diagnosis of Alzheimer’s before clinical signs and symptoms appear, as it is likely that early treatment will be critical as therapies become available.

Source: NIH

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People With Early onset Alzheimer’s Describe What Life Is Like

Posted by on Aug 26, 2011 in Early Onset Alzheimer's Disease, Elayne Forgie, Living with Alzheimer's, Younger Onset Alzheimer's Disease | 0 comments

I found this story on PBS today and wanted to share it.  Susan Dentzer reports on early onset Alzheimer’s, a degenerative brain disease, and how a forum organized by those suffering from the diagnosis has proven an effective means of coping. 

JIM LEHRER: Finally tonight, dealing with Alzheimer’s disease at an earlier age. Susan Dentzer reports for our Health Unit, a partnership with the Robert Wood Johnson Foundation.

RICHARD BOZANICH: This is just really rough.

SUSAN DENTZER, NewsHour Health Correspondent: Richard Bozanich and Jay Smith spent months planning and preparing. On the big day here in Los Angeles, Bill Bridgwater flew in from Colorado. James Smith and his wife, Juanita, came from Minnesota. And Carol Kirsch and her hud, Howard, drove in from ther aging baby boomers present, you might have thought this gathering was about prepring for retirement, launching a second career,acation home. But iasn’t.

FORUM SPEAKER: This is the largest gathering of people with dementia in one room in our country.

SUSAN DENTZER: In fact, what was billed as the Early Memory Loss Forum was one of the nation’s first-ever gatherings of baby boomers with early-onset Alzheimer’s disease, organized and led by these Alzheimer’s sufferers themselves.

Bozanich, who’s 49, welcomed the crowd on behalf of himself and co-organizer, Jay Smith.

RICHARD BOZANICH: Our motto has always been that this day was by and for persons with early memory loss. So for those of you who are traveling the same road as the two of us, this day is for you.

SUSAN DENTZER: It isn’t known how many Americans have the early-onset form of Alzheimer’s, but estimates range anywhere from 250,000 to 500,000. The cause isn’t fully understood, either, although several genetic mutations are implicated in some cases.

Meanwhile, it’s estimated that 5.1 million Americans now suffer from all forms of the disease, including the type that typically hits people 65 and older. With the population aging, the number of sufferers with all forms of Alzheimer’s could more than triple over the next 40 years.

We wanted to know more about what it’s like to be struck by Alzheimer’s in the prime of life, so we sat down for a conversation with this group, all suffering from early-onset Alzheimer’s. All have worked with the National Alzheimer’s Association and are among the nation’s most vocal spokespersons for the urgency of fighting the disease.

This diagnosis came along when you all were at the peak of your careers and the peak of your capabilities.

BILL BRIDGWATER: Prior to the onset of my Alzheimer’s at age 48, I was an information technology executive, and I had held senior-level positions at numerous multibillion-dollar companies.

RICHARD BOZANICH: I was managing editor of Daily Variety, which is an entertainment trade publication.

JAMES SMITH: I was an information technology director for a Fortune 100 company, a global company. I referred to it as our charmed little life, because everything just seemed to be firing on all cylinders.

Developing strange symptoms

SUSAN DENTZER: Each described how these seemingly charmed lives were suddenly interrupted by a bizarre range of symptoms, as Alzheimer’s, a degenerative brain disease, progressively killed neurons in different parts of the brain.As they lunched at the conference, they recalled how they’d sometimes exhibit the classic signs of memory loss, but often the symptoms were altogether different. Work colleagues were among the first to notice.

JAMES SMITH: People would ask me, they would say, “Well, why weren’t you at the meeting?” And I said, “Well, there was no meeting that I’m aware of.” And they said, “Well, you called the meeting. You should be aware of it.”

BILL BRIDGWATER: One of the things that was just driving me to distraction was insomnia. I could not sleep at night. I would get up and do 50 push-ups, 50 sit-ups, 50 leg kicks with each leg, and do everything I could to just drain myself. I laugh and tell people that I didn’t get much sleep, but I was in the best shape of my life.

CHUCK JACKSON: My arm would be sitting here and suddenly it would just shoot up and hit me in the head almost. And my legs would kick.

RICHARD BOZANICH: I was just bumping into walls and bumping into partitions. And, you know, you see a wall in front of you, and the obvious thing is to either go left or right, and I would just walk straight into the wall as if it weren’t there.

Conflicting diagnoses

SUSAN DENTZER: The group told us about dozens of visits to doctors who handed out conflicting diagnoses. Jay Smith, a successful architect who is not related to James Smith, had helped design courts and other facilities for California’s justice system.JAY SMITH, Alzheimer’s Sufferer: I thought I had a brain tumor, so I went to the neurologist, and I didn’t have a brain tumor. He said he thought I had a benign condition called migraine that doesn’t always cause headaches.

JAMES SMITH: For me, the initial diagnosis was depression. Then they shifted over and thought, well, maybe it’s a movement disorder, like MS or something like that. And for a while, they were thinking it might be Huntington’s disease.

SUSAN DENTZER: Most of the group told us the correct diagnosis was only arrived at when they finally got a battery of neuropsychological tests and a PET scan of the brain.

But for Chuck Jackson, who most recently worked as a counselor to laid-off workers, the diagnosis was far easier.

CHUCK JACKSON: We’re one of those groups of families that have the highest rate or incidence of Alzheimer’s in their family. I watched my mother go through it when I was — I was 13 at the time. And when she died at the age of 50, I knew what was coming.

SUSAN DENTZER: In fact, out of his mother’s family of 14 children, 12 died of the disease, thanks to inherited mutation in a gene called PSEN2. Now Jackson and his older brother both have Alzheimer’s.

The group members told us that getting the diagnosis prompted a range of reactions.

JAY SMITH: It came as a shock, because I hadn’t thought about Alzheimer’s or memory loss up to that point, and relief to have an answer, “I can now focus on my life knowing what’s wrong.”

CAROL KIRSCH, Alzheimer’s Sufferer: I just refused to believe it. I just said, “No, this can’t be.” I knew enough about it that I was scared. I was scared.

SUSAN DENTZER: James Smith and his wife, Juanita, spoke at the conference about how they reacted after getting the diagnosis.

JAMES SMITH: We would just lay in bed together, and hold each other, and cry, and really not know — it felt like you were in a maze and all the doors just suddenly slammed shut. And there’s just no path that takes you anywhere. I remember it as being one of the — probably one of the darkest periods of our entire life.

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Legendary Coach Pat Summitt Faces Early Onset Alzheimer’s With Strength & Bravery

Posted by on Aug 24, 2011 in diagnosis, Early Onset Alzheimer's Disease | 0 comments

Yesterday, Pat Summitt, college basketball’s winningest coach, said in an interview that she had been diagnosed with early onset Alzheimer’s.  At just 59 years old, her strength and bravery as she begins to fight this disease is truly admirable.

She said she first noticed something was wrong when she would forget little things like what time she had to get in to the office and her son noticed that she had started asking the same questions more than once.
In a recent interview, Coach Summitt said that her initial reaction to learning she had a progressive condition that could impair her mental acuity was one of anger and denial. She went on to say that now that she has accepted her diagnosis, she hopes it will inspire her more and that she will not let it her from living her life and from coaching.
You can learn more about the symptoms of early onset Alzheimer’s disease here.

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Huge New Screening (and drug treatment) Push for Alzheimer’s Disease

Posted by on Aug 22, 2011 in Alzheimer's Care West Palm Beach, alzheimer's disease west palm beach, Early Onset Alzheimer's Disease, Medication for Alzheimer's, treatment for Alzheimer's, Younger Onset Alzheimer's Disease | 0 comments

(NaturalNews) Alzheimer’s researchers are pushing for the disease to be redefined so that treatment can begin years earlier than under current practices.

Alzheimer’s disease is the most common form of dementia, and can currently be conclusively diagnosed only with an autopsy. It already affects more than 26 million people around the world, and this number is expected to triple by 2050.
“The symptoms of Alzheimer’s disease are progressive mental deterioration characterized by an inability to carry out daily activities, a loss of cognitive functions, and a loss of memory functions,” writes Tom Bohager in his book Everything You Need to Know About Enzymes.
“Extensive research studies indicate that the causes of Alzheimer’s disease can include genetic factors, age, environmental factors, chronic exposure to aluminum and/or silicon, and increased oxidative damage due to long-term toxic exposure.”
Dementia cannot currently be cured, but some drugs have been developed that attempt to slow its progression. Many of these drugs have limited effectiveness in the later stages of the disease, however, when symptoms have become severe.
For this reason, researchers from the International Working Group for New Research Criteria for the Diagnosis of Alzheimer’s Disease published an article in The Lancet calling for a new definition of Alzheimer’s.
Under the proposed definition, an Alzheimer’s diagnosis could be made in any patient suffering from episodic memory impairment who also tested positive for at least one biomarker that scientists have associated with the disease.
Biomarkers are chemicals in the body that imply the presence of a certain condition. One of the most well-known biomarkers is the prostate specific antigen (PSA), which is correlated with inflammation of the prostate gland.
“It’s very important for us to move from the old way of seeing Alzheimer’s disease to a new one that incorporates the importance of biomarkers,” said the working group’s Bruno Dubois. “There is no longer a reason to wait until patients have developed full-blown dementia.”
Sources for this story include:….
by David Gutierrez, staff writer-Natural News
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If you are worried about a loved one call us at 1-800-209-4342 for a free Assessment in Palm Beach, Broward & Martin County. You can also call our  Crisis line anytime 24 hours a day at 1-800-209-4342 for help with loved ones with Alzheimer’s
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